diff --git a/gdb/breakpoint.c b/gdb/breakpoint.c
index bff3bac7d1a..15f4ae2131c 100644
--- a/gdb/breakpoint.c
+++ b/gdb/breakpoint.c
@@ -5340,6 +5340,8 @@ bpstat_check_breakpoint_conditions (bpstat *bs, thread_info *thread)
   /* Evaluate extension language breakpoints that have a "stop" method
      implemented.  */
   bs->stop = breakpoint_ext_lang_cond_says_stop (b);
+  if (b->disposition == disp_del_at_next_stop)
+    disable_breakpoint(b);
 
   if (is_watchpoint (b))
     {
diff --git a/gdb/testsuite/gdb.python/py-watchpoint.c b/gdb/testsuite/gdb.python/py-watchpoint.c
new file mode 100644
index 00000000000..4e1760bb05b
--- /dev/null
+++ b/gdb/testsuite/gdb.python/py-watchpoint.c
@@ -0,0 +1,27 @@
+/* This testcase is part of GDB, the GNU debugger.
+
+   Copyright 2022 Free Software Foundation, Inc.
+
+   This program is free software; you can redistribute it and/or modify
+   it under the terms of the GNU General Public License as published by
+   the Free Software Foundation; either version 3 of the License, or
+   (at your option) any later version.
+
+   This program is distributed in the hope that it will be useful,
+   but WITHOUT ANY WARRANTY; without even the implied warranty of
+   MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+   GNU General Public License for more details.
+
+   You should have received a copy of the GNU General Public License
+   along with this program.  If not, see  <http://www.gnu.org/licenses/>.  */
+
+#include <stdio.h>
+
+int
+main (void)
+{
+  int i;
+  for (i = 0; i < 3; i++)
+    printf ("%d", i);
+  return 0;
+}
diff --git a/gdb/testsuite/gdb.python/py-watchpoint.exp b/gdb/testsuite/gdb.python/py-watchpoint.exp
new file mode 100644
index 00000000000..ac58d75c523
--- /dev/null
+++ b/gdb/testsuite/gdb.python/py-watchpoint.exp
@@ -0,0 +1,48 @@
+# Copyright (C) 2022 Free Software Foundation, Inc.
+#
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 3 of the License, or
+# (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+# GNU General Public License for more details.
+#
+# You should have received a copy of the GNU General Public License
+# along with this program.  If not, see <http://www.gnu.org/licenses/>.
+
+# Check that Watchpoints are deleted after use.
+
+load_lib gdb-python.exp
+
+standard_testfile
+
+if {[prepare_for_testing "failed to prepare" $testfile $srcfile]} {
+    return -1
+}
+
+# Skip all tests if Python scripting is not enabled.
+if { [skip_python_tests] } { continue }
+
+if ![runto_main] then {
+    return 0
+}
+
+# For remote host testing
+set pyfile [gdb_remote_download host ${srcdir}/${subdir}/${testfile}.py]
+
+gdb_test_no_output "set can-use-hw-watchpoints 0" "Don't use hardware watchpoints"
+gdb_test "python print(len(gdb.breakpoints()))" "1" "check default BP count"
+gdb_test "source $pyfile" ".*Python script imported.*" \
+    "import python scripts"
+gdb_test "python print(len(gdb.breakpoints()))" "2" "check modified BP count"
+gdb_test_sequence "continue" "run until program stops" {
+    "Watchpoint Hit: ."
+    "\[\r\n\]+Watchpoint . deleted because the program has left the block in"
+    "\[\r\n\]+which its expression is valid\."
+    "Watchpoint Hit: ."
+    "\[\r\n\]+012\\[Inferior 1 \\(process .*\\) exited normally\\]"
+}
+gdb_test "python print(len(gdb.breakpoints()))" "1" "check BP count"
diff --git a/gdb/testsuite/gdb.python/py-watchpoint.py b/gdb/testsuite/gdb.python/py-watchpoint.py
new file mode 100644
index 00000000000..ce5dee118ad
--- /dev/null
+++ b/gdb/testsuite/gdb.python/py-watchpoint.py
@@ -0,0 +1,30 @@
+# Copyright (C) 2022 Free Software Foundation, Inc.
+#
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 3 of the License, or
+# (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+# GNU General Public License for more details.
+#
+# You should have received a copy of the GNU General Public License
+# along with this program.  If not, see <http://www.gnu.org/licenses/>.
+
+
+class MyBreakpoint(gdb.Breakpoint):
+    def __init__(self, *args, **kwargs):
+        gdb.Breakpoint.__init__(self, *args, **kwargs)
+        self.i = 0
+
+    def stop(self):
+        self.i += 1
+        print("Watchpoint Hit:", self.i)
+        return False
+
+
+MyBreakpoint("i", gdb.BP_WATCHPOINT)
+
+print("Python script imported")
